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The effect of Brotowali (Tinospora crispa (L) Miers ex Hook .f. & Thems ) extracts on Degranulation Mast cell.

Hainil, Sri and Aldi, Yufri (2016) The effect of Brotowali (Tinospora crispa (L) Miers ex Hook .f. & Thems ) extracts on Degranulation Mast cell. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7 (5). pp. 1502-1507. ISSN 0975-8585

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Abstract

Mast cell degranulation that induced by subtance 48/80 at dose of 10 μg/ml from Brotowali extract (Tinospora crispa (L) Miers ex Hook .f. & Thems ) using invitro methode has been investigated. Extract of Brotowali as preparation was maceration using ethanol and fraction of petroleum ether,chloroform and water.The result of study showed that chloroform fraction of Brotowali with concetration of 5 μg/ml to 625 μg/ml inhibited the mast cell degranulation that induced by 10 μg/ml substance 48/80 with significanty (p≤0,01). Keywords: Tinospora crispa (L) Miers ex Hook .f. & Thems; Mast cell degranulation; subtance 48/80; fraction.

Item Type: Article
Subjects: R Medicine > RM Therapeutics. Pharmacology
Unit atau Lembaga: Fakultas Farmasi
Depositing User: Dr Yufri Aldi, M.Si. Apt.
Date Deposited: 30 Jan 2017 02:18
Last Modified: 30 Jan 2017 02:18
URI: http://repository.unand.ac.id/id/eprint/23885

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