Nila, Kasuma
(2017)
THE SALIVARY IL-1? AS PERIODONTAL DISEASE DIAGNOSTIC MARKER.
In: 12th ADRI 2017 International Multidisciplinary Conference and Call for Paper, Bogor, March 30 – April 01, 2017 , March 30 – April 01, 2017 , Bogor, Indonesia.
Abstract
Abstract. Periodontal disease is preceeded from gingivitis, if not treated appropriately this inflamation disease will be worse . It turns into periodontitis . more severe . Periodontitis is characterized by loss of tissue attachment and alveolar bone destruction. Interleukin-1? (IL-1?) is one of the main cytokines related to pathology of inflammatory and potentially stimulate bone resorption. Saliva is oral fluid that may reflect the levels of IL-1? as a biological marker of inflammation in periodontal disease. The purpose of this study was to determine the difference between the levels of IL-1? GCF contained in the present in saliva . Samples have as many as 54 people, divided into three main groups, 18 patients with mild gingivitis, 18 with mild periodontitis patients and 18 healthy controls with ages ranging between 17-45 years. Unstimulated whole saliva were collected, then IL-1? levels were measured using ELISA. The average levels of IL-1? contained in saliva by Ramfjord PDI group has significant difference (p <0.05). There are differences between the levels of IL-1? contained in saliva on healthy group, mild gingivitis, and mild periodontitis.
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