Isolasi Senyawa Larvasida Dari Fraksi Nonpolar Spon Laut Axinella carteri Dendy

Handayani , Dian and A, Almahdy and Farlian , Ali (2014) Isolasi Senyawa Larvasida Dari Fraksi Nonpolar Spon Laut Axinella carteri Dendy. Jurnal Sains dan Teknologi Farmasi, 11 (2). pp. 94-100. ISSN 1410-0177

	PDF (Isolasi Senyawa Larvasida Dari Fraksi Nonpolar Spon Laut Axinella carteri Dendy) - Published Version Available under License Creative Commons Public Domain Dedication. Download (514Kb)
	Postscript (Isolasi Senyawa Larvasida Dari Fraksi Nonpolar Spon Laut Axinella carteri Dendy) - Published Version Available under License Creative Commons Public Domain Dedication. Download (2169Kb)

Abstract

Two active larvacidal compopunds (AC-H221) and (AC-H32) have been isolated from the n-hexane fraction of the Marine Sponge Axinella carteri Dendy, using bioassay guided by “The Yellow Fever Mosquito Larvae Microtiter Plate Assay” method. Isolation and purification of the compounds were done by chromatography method followed by recrystalitation. Compound AC-H221 was isolated as tellowish oil with specific odour. Compound AC-H32 was obtained as white oomph, m.p. 173-174oC. Both compounds were tested against Mosquito larvae of Culex larva and showed the LC¬50 53.75 and 79.8 ppm, respectively. Identification and characterization of the active compounds were confirmed by chemical reaction and infrared spectrum. Based on spectral data chemical reaction, both compound were identified as terpenoid. Keywords : Axinella carteri. Larvacidal activity, marine sponge, isolation

Actions (login required)

View Item