Daun Tanaman Akar Mambu (Connarus grandis Jack.) Sebagai Obat Hipertensi : Efektivitas Ekstrak Etanolnya Pada Tikus Hipertensi 2k1c Goldblatt

Armenia, Armenia and Welmidayani, Welmidayani and Yuliandra, Y. and Rusdi, Rusdi (2014) Daun Tanaman Akar Mambu (Connarus grandis Jack.) Sebagai Obat Hipertensi : Efektivitas Ekstrak Etanolnya Pada Tikus Hipertensi 2k1c Goldblatt. Jurnal Sains dan Teknologi Farmasi, 12 (2). ISSN 1410-0177

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Abstract

An anti hypertensive effect of Connarus grandis Jack. leaves ethanolic extract has been investigated on anesthetized two kidney one clipt (2K1C) Goldblatt hypertensive rats. Four groups of animals were treated with the extract at doses of 10, 20, 40, and 80 mg/kg BW intra peritoneally. These doses were repeated every half an hour. Blood pressure (systolic, diastolic mean) and heart rat were measured ten minutes after each dose.

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