PENGARUH TAMOXIFEN TERIIADAP STRUKTUR GINJAL DAN HIPOFISA MENCIT (Mus musculus)

Gani , Yarnelly and Munir, Warnety (2010) PENGARUH TAMOXIFEN TERIIADAP STRUKTUR GINJAL DAN HIPOFISA MENCIT (Mus musculus). JUMPA JURNAL MATEMATIKA DAN PENGETAHUAN ALAM, 2 (1). ISSN 0853-0033

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Abstract

The influence of Tamoxifen, a synthetic hormon that competes with estrogen for the receptors, on the structure of kidney and anterior pituitery was studied using mice (Mus musculus) as experimental animals. This study revealed that lumen of bowman's capsules of animals treated with 0,01 mg Tamoxifen dayly for two months become thinner and two to three gromeruli which do not have Bonanan's capsule appear in cloce contact one to another. This study also showed that the activity of anterior pituitary decreases, shown by low number of basophil cells.

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