Produksi Antibodi pada Tikus Putih Betina Rattus Norvegicus dengan Injeksi Vaksin Hepatitis B

Abbas, Nila Djuita and Aziz, Rusdi and Neyla, Neyla (2014) Produksi Antibodi pada Tikus Putih Betina Rattus Norvegicus dengan Injeksi Vaksin Hepatitis B. Jurnal Sains dan Teknologi Farmasi . ISSN 1410 – 0177

	PDF Download (296Kb)
	Postscript Download (1305Kb)

Abstract

The antibody production by the white rat Rattus norvegicus after boostering increased twenty times than that of the non booster male white rate group. In this study, an injection of HbsAg was given to two groups of white rat Rattus norvegicus (A & B). Group A consisted of 3 females white rat as the experimental object and group B consisted of 3 male white rat as control. HbsAg was given intramuscularly to both groups at day 1st ,9th, 15 th and 19th . The blood serum was absorbed ten times in three day interval. The antibody production in blood serum was detected by the ELISA (Enzyme Link Immunosorbent Assay) method. The results showed,that the production of antibodies rvas much highes in the female white rat than the group. An increase in the antibody was seen at day 5 th in the female group in the amount of 83 times than the first sample; the highest antibody production was found after the first booster for about 9555 IU/ml. The highesf antibody production of the male group was only 491 IU/ml at day 20th.

Actions (login required)

View Item