Pengaruh Kadar Air di Dalam Dasar Salep Vaselin Lemak Bulu Domba terhadap Profil Liberasi Asam Salisilat dan Asam Benzoat

Hosiana , Vinny and Lucida, Henny and Sumarni, Irta (2010) Pengaruh Kadar Air di Dalam Dasar Salep Vaselin Lemak Bulu Domba terhadap Profil Liberasi Asam Salisilat dan Asam Benzoat. Jurnal Sains dan Teknologi Farmasi, 8 (2). ISSN 1410 – 0177

	PDF (Pengaruh Kadar Air di Dalam Dasar Salep Vaselin Lemak Bulu Domba terhadap Profil Liberasi Asam Salisilat dan Asam Benzoat) - Published Version Available under License Creative Commons Public Domain Dedication. Download (511Kb)
	Postscript (Pengaruh Kadar Air di Dalam Dasar Salep Vaselin Lemak Bulu Domba terhadap Profil Liberasi Asam Salisilat dan Asam Benzoat) - Published Version Available under License Creative Commons Public Domain Dedication. Download (2086Kb)

Abstract

The influence of water content in vaselin-adepslanae ointment base on the liberation profile of salicylic and benzoic acid has been investigated. The water content of the ointment base was 10.25 and 40 %. A simple diffusion cell with cellulose membrane (Whatman®) as a semi permeable membrane was used. The absorbance salicylic and benzoic acid liberated were measured at predetermined time interval by UV-visible spectrophotometer at 227 nm and 229 nm and the concentration of each was then calculated by using spectrophotometric multicomponent method. The results indicated that the ointment base containing 25 % of water showed maximum liberation of salicylic and benzoic acid. Statistical analysis showed that the water contentof vaseli-adeps lanae ointment base influenced the liberation profile of salicylic and benzoic acid significantly at p<0.01. Keywords : dasar salep vaselin-lemak bulu domba, profil liberasi.

Actions (login required)

View Item