Pengaruh Pemberian Akut Ekstrak Etanol Daun Capo (Blumea balsamifera (L.)DC) Terhadap Gambaran Morfolofis dan Histologi Hati Mencit Putih Jantan

Arifin, Helmi and Widianingsih, Ice and Marusin, Netty (2014) Pengaruh Pemberian Akut Ekstrak Etanol Daun Capo (Blumea balsamifera (L.)DC) Terhadap Gambaran Morfolofis dan Histologi Hati Mencit Putih Jantan. Jurnal Sains dan Teknologi Farmasi, 12 (2). ISSN 1410-0177

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Abstract

Hepatotoxicity tests of the ethanolic extract of Blumea balsamifera (L.)DC leaves on male mice has been done. The ethanolic extract was given intra peritoneally (i. p.) once a day at the doses of 2; 2.5; 3.2; 4 g/kg of the body weight. Vehlcel Na-CMC 1 % was to the control mice. Some parameters were observed after 14 days i. e the changing colour and texture of the liver, the percentage damage of central vein of the liver, the condition of hepatic cell, sitoplasm, nucleus and sinusoids of liver. The results showed the changing of colour and texture of the liver.

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